Patient Outcome Prediction and Simulation Platform

Identify the right patient.
For the right drug.
Every time.

KolateAI's agentic AI platform predicts and simulates individual patient outcomes: drug response, adverse events, and disease risk. It works quickly, accurately, and at scale, so your team can target the best-fit patients instead of guessing.

Live Prediction ConfidenceMODEL ACTIVE
Atopic Dermatitis
Drug Response ··· Prediction Confidence···
Ocular Side Effects Risk ··· Prediction Confidence···
Type 1 Diabetes
Patient 1 Disease Risk ··· Prediction Confidence···
Patient 2 Disease Risk ··· Prediction Confidence···
Illustrative output from KolateAI Predict across Atopic Dermatitis and Type 1 Diabetes cohorts

Resident company of Johnson & Johnson Innovation, JLABS @ NYC, and backed by

Stratum Biosciences
NAMina Bioscience
Rutgers University
Meet the Drapers
ERA
NJEDA
BioNJ
TiE50
MTPPI
IIT Startups
Health Engine
Microsoft for Startups
PharmStars
Our Solution

A unified agentic AI platform for patient-level outcome prediction & simulation.

KolateAI turns fragmented patient-level data (proprietary, external, real-world, and trial) into individual outcome predictions and digital twins, orchestrated by disease-specific models.

01

Aggregates Multi-Modal Data

Proprietary, external, and synthetic real-world & trial data: structured, notes, and imaging.

02

Integrates Patient History

Builds a full longitudinal treatment narrative and trajectory per patient.

03

Orchestrates Disease-Specific Models

Trains and auto-selects the best-fit model per therapeutic area using KCV, a composite score balancing accuracy, F1, AUC, and explainability.

04

Generates Digital Twins

Simulates each patient under alternative therapies for head-to-head, no-new-trial-needed comparisons.

Product 01

KolateAI Predict

Targeted patient-level prediction of drug response, adverse events, and disease risk, before a trial starts or a prescription is written.

Up to 97.8% F1 in validated models →
Product 02

KolateAI Compare

Emulated head-to-head comparison of alternative therapies using synthetic control arms, generating RWE without a new prospective trial.

4 synthetic head-to-heads published →
Product 03

KolateAI Co-pilot

An interactive assistant for study physicians & scientific staff to query predictions, study actuals, and protocol documentation in real time.

Real-time study management →
See It In Action

A quick look inside the platform.

Three screens from the actual KolateAI workspace: cohort building, best-fit prediction, and therapy comparison.

Cohort builder showing explicit inclusion and exclusion criteria

Define a cohort in minutes

Explicit inclusion/exclusion criteria, live cohort size, and descriptive stats, with no data engineering required.

Prediction results showing cohort-level and patient-level response

Get a best-fit prediction

The best model is pre-selected automatically: cohort- and patient-level response, ready to filter and export.

Therapy comparison showing digital twin simulation results

Compare therapies in-silico

Digital twins weigh your target therapy against alternatives, for one patient or a whole cohort.

Proof in Practice

Validated across therapeutic areas.

High-level results from KolateAI work samples and pilot studies with design partners. Details are in full on the Studies page.

Immunology, Dermatology

Atopic Dermatitis Therapy Response

Identified treatment-resistant patients predicted not to respond to TCS or Dupilumab, before they were prescribed.

97.8%F1 Score
1,400Patients
Oncology

CAR T-Cell Therapy Comparison

Synthetically compared two CD19-directed CAR T-cell therapies for relapsed/refractory Large B-Cell Lymphoma on a common patient group.

84%Accuracy
520Patients
Metabolic Disease

Diabetes Risk Screening

Predicted patients most at-risk for Type 1, LADA, and Type 2 Diabetes from routine clinical data (including regular exams and personal health surveys), enabling earlier, targeted intervention.

99.6%AUC (T1D)
57,204Patients
Our Customers

What design partners are saying.

"We learnt something new about our drug: that it directly benefited certain metabolic syndrome patients, while making the condition worse in others, and are now able to target the right patients for our upcoming clinical trial."

Clinical Development Head, leading biotech

"KolateAI made it simple for us to generate RWE comparing our new drug with prior alternatives, using their head-to-head therapy comparison tool."

HEOR Executive Director, biopharma
Get Started

Ready to bring precision medicine to your program?

Talk to us about a proof-of-concept for your therapeutic area.

Contact us for a POC